Evaluation of Hypoglycemic Potential Effect of Phyllanthus Niruri in Alloxan Induced Diabetic Male Swiss Albino Mice

Authors

  • Pabbathi Venkata Sravani Department of Pharmacology, Ratnam Institute of Pharmacy, Pidathapolur (V&P), Muthukur (M), SPSR Nellore District – 524 346 Author
  • C. Madhavi Latha Department of Pharmacology, Ratnam Institute of Pharmacy, Pidathapolur (V&P), Muthukur (M), SPSR Nellore District – 524 346 Author
  • Y. Prapurna Chandra Department of Pharmacology, Ratnam Institute of Pharmacy, Pidathapolur (V&P), Muthukur (M), SPSR Nellore District – 524 346 Author

DOI:

https://doi.org/10.30904/j.wjpbt.2023.4552

Keywords:

phyllanthus niruri, antidiabetic activity, Alloxan, hypoglycemic, blood glucose, albino mice

Abstract

The present study on diabetes was carried out on the male swiss albino mice. The project was aimed to study the antidiabetic activity of leaf extracts of phyllanthus niruri in Alloxan induced diabetes. Serum blood glucose levels were anazyled by using auto analyzer. Histopathological studies were carried out to confirm the biological changes. In the present study administration of Alloxan significant increase of blood glucose levels in Diseased, Standard, Ethanolic and Aqueous groups. Administration of seed extracts of phyllanthus niruri shown significant decrease in the ethanolic and Aqueous groups. Thus seed extracts of phyllanthus niruri shows hypoglycemic potential effect.

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Published

2023-09-25

Issue

Vol. 10 No. 02 (2023): WJPBT

Section

Articles

License

Copyright (c) 2025 Author

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

Pabbathi, V. S., C, M. L., & Y, P. C. (2023). Evaluation of Hypoglycemic Potential Effect of Phyllanthus Niruri in Alloxan Induced Diabetic Male Swiss Albino Mice. World Journal of Pharmacy and Biotechnology, 10(02), 91-95. https://doi.org/10.30904/j.wjpbt.2023.4552