A Study on Assessment of Corticosteroid Drug Induced Psychosis and Treatment Based Outcomes

Abstract

Introduction: Corticosteroids are integral to treatment across various medical domains. They are synthetic analogs of natural steroid hormones produced by the adrenal cortex like glucocorticoids (GCs), mineralocorticoids and sexual hormones. Aim: The study aimed to assess corticosteroid drug induced psychosis and treatment based outcomes. Methodology: The prospective observational study was carried out for a period of 6 months. The study was conducted in General Medicine department in a tertiary care hospital. A written and informed consent was obtained from the recruited patients. A Total of 85 patients were enrolled in the study. Results & Discussion: In our study 46-55 years age patients were more 33(28.82%) compared to other ages.  In our study Male patients were more 51 (60 %), compared to Female patients were 34(40 %).  The oral route drug administration patients were more 56 (65.88%), compared to parenteral route drug administration patients were 29(34.11%). The Management of steroid drug induced psychosis includes Psychological support patients were more 39(45.88%) compare to Psychological therapy patients were 22(25.88%), Psychological interventions patients were 24(28.23%). The Treatment for steroid drug induced psychosis includes Lithium prescribed patients were more 25 (29.41%) compare to other prescribed drugs. Conclusion: The effective diagnosis primarily involves excluding other potential causes, while prevention primarily focuses on minimizing dosages and avoiding the unnecessary prolongation of drug treatment.  Although steroid-induced psychosis can typically be managed by tapering and discontinuing the offending steroid, patients may still experience persistent mood disturbances and psychosis.