Review on Microencapsulation Drug delivery Systems

Abstract

Microencapsulation is a well-designed controlled or sustained drug delivery system. The advantageous of this system to overcome the some problems in conventional therapy and to enhance the therapeutic efficacy and bioavailability of given drug. It is the reliable means to deliver the drug to the target site with specificity, if modified, and to maintain the desired concentration at the site of interest without untoward effects. Microencapsulation is a process whereby small discrete solid particles or small liquid droplets are surrounded and enclosed by an intact shell. Many different active materials like drugs,  pesticides, flavours, enzymes,  vitamins and catalysts have been successfully encapsulated microcapsules made from a  variety of polymeric and non polymeric materials like poly(ethylene glycol), poly(methacrylate), poly(styrene), cellulose, poly (lactide), poly(lactide-co-glycolide), gelatin and  acacia, etc. It is a new technology that has wide applications in pharmaceutical industries, agrochemical, food industries and cosmetics. As it is better drug delivery system than conventional drug delivery system with minimum side effect and having targeted action. The present review focused on advanced techniques and applications of microencapsulation drug delivery system.