In-vitro Anti-arthritic Activity of Leaves of Momordica Charantia Linn.,

Authors

  • P. Gobala Krishnan Professor and Principal, Vagdevi College of Pharmacy and Research Centre, Brahmadevam Village, Muthukur Mandal, Nellore -524346. Author
  • Vonteru Muni Sekhar Associate Professor, Vagdevi College of Pharmacy and Research Centre, Brahmadevam Village, Muthukur Mandal, Nellore -524346. Author
  • V. Hemanth Kumar Associate Professor, Vagdevi College of Pharmacy and Research Centre, Brahmadevam Village, Muthukur Mandal, Nellore -524346. Author
  • G. Sadik Assistant Professor, Vagdevi College of Pharmacy and Research Centre, Brahmadevam Village, Muthukur Mandal, Nellore -524346 Author

Keywords:

Anti-arthritic activity, Momordica charantia, Karela, HRBC

Abstract

The present study is aimed to evaluate the anti-arthritic activity of ethanolic extract of Momordica charantia leaves (EEML) by two in-vitro models i.e. human red blood cell (HRBC) membrane stabilization and inhibition of protein denaturation. The standard drug was diclofenac sodium. The results of both models showed concentration dependent inhibition of protein (egg albumin) denaturation as well as stabilization towards HRBC membrane. On the basis of present findings, it can be concluded that EEML showed anti-arthritic activity due to presence of phytocompounds such as flavonoids, alkaloids, tannins etc.

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Published

2024-05-05

Issue

Vol. 12 No. 1 (2024): IJPNM

Section

Articles

License

Copyright (c) 2024 Author

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

P, G. K., Vonteru , M. S., V, H. K., & G, S. (2024). In-vitro Anti-arthritic Activity of Leaves of Momordica Charantia Linn.,. International Journal of Pharmacy and Natural Medicines, 12(1), 22-25. https://pharmaresearchlibrary.org/journals/index.php/ijpnm/article/view/111