Formulation, Development and In-Vitro studies of Sotalol - Gastro Retentive Floating tablets

Authors

  • K. Jacob Isaac Department of Pharmaceutical Technology, K.G.R.L College of Pharmacy, Bhimavaram-534201, Andhra Pradesh, India Author
  • BH. Sri Swetha Department of Pharmaceutical Technology, K.G.R.L College of Pharmacy, Bhimavaram-534201, Andhra Pradesh, India Author
  • D. Raghava Department of Pharmaceutical Technology, K.G.R.L College of Pharmacy, Bhimavaram-534201, Andhra Pradesh, India Author
  • K. Nageswara Rao Department of Pharmaceutical Technology, K.G.R.L College of Pharmacy, Bhimavaram-534201, Andhra Pradesh, India Author

DOI:

https://doi.org/10.30904/

Keywords:

Sotalol, Guar gum, Xanthum gum, HPMC K15 M, Floating tablets

Abstract

In the “present research work gastro retentive floating matrix formulation of Sotalol” by “using various hydrophilic polymers. “Among all the formulations” the formulations prepared by using Xanthan gum were “unable to produce desired drug release, they were unable to” retard “drug release up to 12” hours. The formulations prepared with Methocel K15 M  retarded the drug “release up to 12 hours” in the concentration of  75 mg (ST3).The “formulations prepared with xanthan gum” were “unable to retarded the drug “release for more than 12 hours. Hence they were not considered”.

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Published

2023-10-22

Issue

Vol. 11 No. 02 (2023): JPBR

Section

Articles

License

Copyright (c) 2023 Author

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

K, J. I., BH, S. S., D, R., & K, N. R. (2023). Formulation, Development and In-Vitro studies of Sotalol - Gastro Retentive Floating tablets. Journal of Pharmaceutical and Biological Research, 11(02), 56-60. https://doi.org/10.30904/