Formulation and Evaluation of gastro retentive Tablet of verapamil

Authors

  • U. Shilpa Assistant Professor, Department of Pharmaceutics, Vijay College of Pharmacy, Nizamabad–503003, Telangana, India Author
  • Ch. Suresh Professor and Principal, Vijay College of Pharmacy, Nizamabad–503003, Telangana, India Author
  • G. Sai Prasanna B.Pharm student, Vijay College of Pharmacy, Nizamabad–503003, Telangana, India Author
  • Javeria Khaleel B.Pharm student, Vijay College of Pharmacy, Nizamabad–503003, Telangana, India Author
  • N. Rani B.Pharm student, Vijay College of Pharmacy, Nizamabad–503003, Telangana, India Author
  • R. Kaveri B.Pharm student, Vijay College of Pharmacy, Nizamabad–503003, Telangana, India Author

DOI:

https://doi.org/10.30904/j.ijrpls.2025.4841

Keywords:

Empagliflozin, Mouth Disintegrating Tablets, Superdisintegrants, In Vitro Drug Release, Patient Compliance, UV Spectrophotometry

Abstract

This study developed and evaluated mouth disintegrating tablets (MDTs) of Empagliflozin to enhance patient compliance and rapid drug onset. Using UV spectrophotometry (λmax 225nm in 0.1NHCl), MDTs were prepared via direct compression with superdisintegrants SSG, Crospovidone, and Croscarmellose sodium. All formulations met pharmacopeial standards. Batch F-6 with Crospovidone showed the best performance, releasing 99% of the drug within 30 minutes. The findings confirm the effectiveness of a minimal-excipient, direct compression method for efficient Empagliflozin delivery.

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Published

2025-06-27

Issue

Vol. 13 No. 1 (2025): Volume 13, Issue 1, 2025

Section

Articles

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Copyright (c) 2025 Author

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

U, S., Ch, S., G, S. P., Khaleel, J., N, R., & R, K. (2025). Formulation and Evaluation of gastro retentive Tablet of verapamil. International Journal of Research in Pharmacy and Life Sciences, 13(1), 38-45. https://doi.org/10.30904/j.ijrpls.2025.4841