Phytochemical Screening and Anti-Arthritic activity of Cymbidium species

Authors

  • Guduru Rajeswari Professor & HOD, Department of Pharmacology, Saastra College of Pharmaceutical Education & Research, Varigonda, Nellore, Andhra Pradesh Author
  • Rao Venkata Lakshmi Prasanna B.Pharm 4th year, Saastra College of Pharmaceutical Education & Research, Varigonda, Nellore, Andhra Pradesh Author
  • Chakali Gunavamsi B.Pharm 4th year, Saastra College of Pharmaceutical Education & Research, Varigonda, Nellore, Andhra Pradesh Author
  • Murinni Harathi B.Pharm 4th year, Saastra College of Pharmaceutical Education & Research, Varigonda, Nellore, Andhra Pradesh Author
  • Pulluru Aneesha B.Pharm 4th year, Saastra College of Pharmaceutical Education & Research, Varigonda, Nellore, Andhra Pradesh Author
  • M. Jayasree B.Pharm 4th year, Saastra College of Pharmaceutical Education & Research, Varigonda, Nellore, Andhra Pradesh Author
  • Gorla Charishma B.Pharm 4th year, Saastra College of Pharmaceutical Education & Research, Varigonda, Nellore, Andhra Pradesh Author
  • Gunji Navya B.Pharm 4th year, Saastra College of Pharmaceutical Education & Research, Varigonda, Nellore, Andhra Pradesh Author

DOI:

https://doi.org/10.30904/

Keywords:

Cymbidium devon odyssey, Cymbidium Sarah Jean, Phytochemical screening, antimicrobial activity, Anti-arthritic activity, Ursolic acid, Protein denaturation

Abstract

The aim of the present study is to explore about the phytochemical and antiarthritic potential of properties Cymbidium devon odyssey and Cymbidium Sarah Jean. Both qualitative and quantitative analyses of ethanol, methanol, chloroform, and aqueous extracts of leaves were conducted, revealing the presence of steroids, terpenoids, tannins, flavonoids, alkaloids, glycosides, saponins, and carbohydrates. Additionally, the anti-arthritic potential of these plants was evaluated, indicating their ability to inhibit protein denaturation a key factor in rheumatoid arthritis pathogenesis suggesting their use in mitigating autoantigen production. The findings contribute a novel phytochemical profile for these species and highlight their potential therapeutic applications. While promising, the study acknowledges limitations such as low extract yield, high cost of solvents, and technical challenges in extraction. Future research should focus on in-vivo studies, high-throughput screening of individual phytocompounds, and exploration of synergistic effects of combined plant extracts for enhanced antimicrobial and anti-inflammatory efficacy.

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Published

2025-06-22

How to Cite

Guduru , R., Rao , V. L. P., Chakali , G., Murinni , H., Pulluru , A., M, J., Gorla , C., & Gunji , N. (2025). Phytochemical Screening and Anti-Arthritic activity of Cymbidium species. International Journal of Pharmacy and Natural Medicines, 13(1), 51-56. https://doi.org/10.30904/