A Study on Detection of Etiological Profile, Diagnostic Examination and Treatment for Osteosarcoma in a Tertiary Care Hospital

Abstract

Background: Osteosarcoma demonstrates a bimodal age distribution and most commonly occurs in the extremities. Approximately 75% of osteosarcoma diagnoses occur in patients less than 25 years of age; the average at diagnosis is 20 years. Aim: The study aimed to detection of etiological profile, diagnostic examination and treatment for osteosarcoma in a tertiary care hospital. Methodology: The prospective observational study was carried out for a period of 6 months. The study was conducted in oncology department in a tertiary care hospital. A written and informed consent was obtained from the recruited patients. A Total of 195 patients were enrolled in the study. Results and Discussion: In our study 46-55 years age patients were more 77(39.485%) compared to other ages. The Etiological profile for osteosarcoma includes Rapid bone growth patients were more 95(48.71%) compared to other etiological profiles. Radiation therapy for osteosarcoma includes Yes patients were more 145 (74.35%), compare to No patients were 50 (25.64%). The Symptoms of osteosarcoma includes Bone pain patients were more 134 (68.71%), compare to Joint Swelling patients were 61 (31.28 %). The Diagnosis of osteosarcoma includes Histology of incisional biopsy patients were more 124(63.58%), compare to Radiograph patients were 71(36.41%). The Treatment for osteosarcoma includes Adjuvant chemotherapy patients were more 102(52.30%), compare to other treatment. Conclusion: The routine evaluation of regional lymph nodes in the staging procedure of the Osteosarcoma is therefore necessary to fully comprehend the metastatic behavior of this tumor type. An incisional biopsy of softer outer parts of the Osteosarcoma combined with a core biopsy from the calcified inner part will result in the best chances for accurate diagnosis and directing the right treatment for affected patients.