Preparation and Evaluation of Famotidine Gastroretentive Tablets by Melt Granulation Method

Authors

  • B. Ranganayakulu Associate Professor, Srinivasa Institute of Pharmaceutical Sciences, Proddatur, A.P., India Author
  • Avula Priyanka Srinivasa Institute of Pharmaceutical Sciences, Proddatur, A.P., India Author
  • S. Mohammed Yusuf Associate Professor, Srinivasa Institute of Pharmaceutical Sciences, Proddatur, A.P., India Author

DOI:

https://doi.org/10.30904/

Keywords:

bioavailability, FDDS, gastroretentive drug delivery, Famotidine

Abstract

The present study involves the formulation and evaluation of gastroretentive drug delivery of Famotidine tablets. This type of drug delivery helps to retain the drug in the stomach. The swelling property of the formulation helps to retain the drug in the stomach, by swelling to such an extent so that cannot pass out of the stomach. Drugs that have poor bio-availability because of their limited absorption to the upper gastrointestinal tract can be delivered efficiently into FDDS. Thereby maximizing their absorption and improving their absolute bioavailability. The floating concept can also be utilized in the development to treating various diseases.

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Published

2019-12-29

Issue

Vol. 6 No. 02 (2019): World Journal of Pharmacy and Biotechnology

Section

Articles

License

Copyright (c) 2019 Author

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

B, R., Avula , P., & S. Mohammed, Y. (2019). Preparation and Evaluation of Famotidine Gastroretentive Tablets by Melt Granulation Method. World Journal of Pharmacy and Biotechnology, 6(02), 68-71. https://doi.org/10.30904/